Basic Human Neuroanatomy
A Clinically Oriented Atlas 
Case 24 Answers

1.  Considering this patient’s initial history and examination five years prior to consultation, how precisely can the neurologic lesion be localized at that time?  If precise localization is not possible, list as many levels and/or structures as you can that might produce the same clinical picture.

Dorsal roots of the spinal nerves, spinal (dorsal root) ganglia, posterior horn of the spinal cord on the right side from about C5 to T1.

2.  What is the localizing significance of the findings on the examination of the motor system and the reflexes?

LMN lesion in R>LUE; UMN lesion in R>LLE.  Typical of a cervical spinal cord  lesion.

3.  What is the anatomical basis of the "suspended sensory level" involving pain sensation?

(Anterior) white commissure – Decussating fibers of the spinothalamic tracts cross  here.

4.  Indicate the level of the neurologic lesion in this case and the structures involved by the pathologic process.  Is a single restricted level or segment of the nervous system involved or does the pathologic process span a few segments?  Indicate the side(s) of the lesion and its extent.  A diagram may be helpful in this instance.


Signs or Symptoms
Initial decreased pain, RUE 

Weakness, atrophy, decreased
DTRs, RUE>LUE


Weakness, increased tone, 
increased DTRs, extensor R   
plantar reflex, RLE>LLE

Suspended pain deficit, BUE
Site of Lesion
See #1 above

R>L  anterior horn, C5-T1
(LMN lesion)


R>>L  lateral corticospinal tracts
(UMN lesion)  

 
White commissure, C2-T1


5.  In general, what type of pathologic process do you think is involved in this case?

Chronic, slowly progressive central spinal cord process extending from about C2-T1  and involving the R>L posterior and anterior horns, the white commissure, and the  lateral corticospinal tracts (but sparing the spinothalamic tracts and the posterior  column pathways).


Pathologic Dx
Syringomyelia  (Differential Dx:  Ependymoma)

6.  What diagnostic procedure(s) would you undertake at this point?


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