1. This patient's signs and symptoms constitute a classical
neurologic syndrome. What is the name of that syndrome?
Parkinson
Disease
2. What is the anatomical location of the basic pathologic
process leading to this patient's condition? What anatomical
pathway(s) is involved in this patient's condition?
Substantia
nigra (pars compacta). Nigrostriatal fibers
3. What neurotransmitter systems are involved in the
manifestations of this syndrome, and which manifestations are
associated with which neurotransmitters?
Decreased
dopamine leads to Parkinsonian Sx. Of course, other
neurotransmitters and other parts of the basal nuclei connections are
also involved in producing the signs and symptoms of Parkinson disease.
4. In general, what type of pathologic process is involved in
this syndrome?
Degenerative
5. What diagnostic procedure(s) would you undertake at this point?
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