Basic Human Neuroanatomy
A Clinically Oriented Atlas 


Case History #64

Date of Admission: 10-7-1988


HISTORY OF PRESENT ILLNESS:

This 17-year-old right-handed white female high school student was admitted to the hospital for evaluation of left-sided weakness.  Five days prior to admission, the patient developed a cold with a runny nose and nasal congestion.  Three days prior to admission, she noted that she was tripping over her left foot when she attempted to walk.  The next day, she felt that the entire left side of her body was numb, and her father told her that the left side of her mouth did not seem to be working as well as the right side.  At that point, the symptoms seemed to stabilize and mainly affected her walking and coordination of her left upper limb.  She was admitted to the hospital for further observation and investigation.

NEUROLOGICAL EXAMINATION:

Mental Status Exam:  Intact.

Cranial Nerves:  Cranial nerve examination was normal except for the following.  There was weakness of the lower facial muscles on the left side, but the patient was able to close her eyelids tightly and wrinkle her forehead symmetrically on both sides.

Motor System:  There were no areas of focal muscular atrophy or fasciculations.  Muscle tone was normal in all 4 limbs.  Muscle power was normal on the right side.  On the left side, there was a moderate degree of weakness (4/5) involving all muscle groups in the upper and lower limbs, with the upper limb being slightly worse than the lower limb.

Reflexes:  Deep tendon reflexes were normal (2/4) and symmetric in the upper limbs.  In the lower limbs, the knee jerks were 2/4 on the right and 3/4 on the left, and the ankle jerks were 1/4 on the right and 2/4 on the left.  Plantar reflexes were flexor on the right and extensor on the left.

Sensory System:  Sensory examination was entirely normal in all 4 limbs.

Cerebellar Function:  Intact on the right side.  On the left side, cerebellar tests were essentially intact, although somewhat difficult to interpret because of the patient’s weakness. 

Gait and Stance:  Regular gait was performed with circumduction and a mild degree of spasticity involving the left lower limb.  Tandem gait was difficult due to the left lower limb weakness.  The Romberg test was negative.


Questions

1.  Is the weakness on the left side of the face of the upper motor neuron or lower motor neuron type?

2.  Is the weakness on the left side of the body of the upper motor neuron or lower motor neuron type?

3.  What specific structure is involved by the pathologic process to produce the patient’s left facial weakness? 

4.  What specific structure is involved by the pathologic process to produce the patient’s left hemiparesis? 

5.  Is it possible to specifically localize the lesion in this case?  If so, where is the lesion localized, including the side.  If not, indicate the possible sites of localization of the lesion, the side involved, and the specific structure(s) involved by the pathologic process. 

6.  This patient’s clinical findings represent a classic neurological syndrome.  What is the name of that syndrome, and what is its usual cause?

7.  In general, what type of pathologic process is involved in this case?

8.  What diagnostic procedure(s) would you undertake at this point?


Answers
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